Phase 3 Clinical Trial of E-Health Behavioral Intervention to Improve Executive Functioning in Adolescents with Epilepsy
This study will test Epilepsy Journey, a multicomponent treatment program designed to equip adolescents with epilepsy with problem-solving skills to manage their executive function challenges.
Sponsor
National Institutes of Health
Subaward from Cincinnati Children’s Hospital
$239,410Principal investigator
Avani Modi
Professor, Division of Behavioral Medicine and Clinical Psychology
Director, Center for Adherence and Self-Management, Cincinnati Children’s Hospital Medical CenterCo-principal investigators
Sonal Bhatia, M.D., and Janelle Wagner, Ph.D.
Medical University of South CarolinaChris Coffey, Ph.D.
University of Iowa
Clinical Trials Statistical and Data Management CenterTracy Glauser, M.D., and Shari Wade, Ph.D.
Cincinnati Children’s Hospital Medical CenterHeather Huszti, Ph.D.
Children’s Hospital of Orange CountyMatthew Schmidt
Associate professor, Department of Workforce Education and Instructional TechnologyActive since
February 2024
Abstract
This study will test Epilepsy Journey, a multicomponent treatment program with web-based modules and telehealth visits, which is designed to equip adolescents (ages 13-17) with epilepsy with problem-solving skills to manage their executive function challenges. This work is relevant to the National Institute of Neurological Disorders and Stroke’s mission to help all people live longer, healthier lives and will ultimately reduce health disparities and improve access to psychosocial care.
Public health relevance statement: This research is of high public health relevance because of the sizable population of adolescents with epilepsy at high risk for lifelong impairments in executive functioning (i.e., skills necessary for goal-directed and complex activities, including problem-solving, initiating, monitoring, organization, planning, self-regulation, and working memory) and quality of life.