Integrative Cardiovascular Physiology Lab
The Integrative Cardiovascular Physiology Laboratory examines vascular function, with an emphasis on the prevention and treatment of cardiovascular diseases. We use experimental tools and approaches from multiple disciplines including physiology, cellular biology, biochemistry, and functional genomics. Our studies involve both human subjects and rodent models of obesity and type 2 diabetes.
Students work in this lab as part of the following programs of study:
- Ph.D. in Kinesiology (emphases in biomechanics and exercise physiology )
- M.S. in Kinesiology (emphases in biomechanics , exercise physiology , and exercise psychology )
- B.S.Ed. in Exercise and Sport Science
Equipment
- Bio-Rad CFX Connect Real Time qPCR system
- Class II Biosafety Cabinet
- Humidified incubator for cell culture experiments
- Immunomagnetic cell separation magnets (EasySep)
- Fluorescent plate reader for studies of intracellular free radical dynamics
- General “wet lab” equipment for cellular/molecular biology work
- Instruments available in the UGA Flow Cytometry Core Facility
- Equipment for testing metabolic and cardiorespiratory responses to exercise in humans (ergometers, metabolic carts, and various devices for noninvasive measurements of cardiovascular function)
Research
Exercise-induced signals for vascular adaptations with emphasis on prevention and treatment of cardiovascular diseases. These “signals” include:
- Hemodynamic forces such as shear stress
- Circulating factors such as endothelial progenitor/stem cells, inflammatory cytokines, and mediators of oxidative stress